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Sildenafil (Viagra) is the most effective oral therapy currently available for erectile dysfunction. Higher doses come with an increased chance of To me that is an excellent sign that it is going away. Sildenafil is an effective option for erectile dysfunction. Erectile dysfunction affects an estimated 18 million men in the U.S. alone. Our medical team can prescribe Cialis 5mg, 10mg, and 20mg. 30 mins. With ED, you're unable to have or maintain an erection. How long effects last. Both tadalafil and sildenafil are similar in nature and belong to the same class of drugs, PDE-5 inhibitors. If youre in doubt about the right dose, speak to a Manual clinician. sildenafil. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay. 12. 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